Bibliography and Author's Preface
Joint Dys References
1. Albert, P. W., Scheer, B. T. and Deuel, H. J., Jr. The Effect of 3-Hydroxyanthranilic Acid on the Excretion of Niacin by the Rat. J. Biol. Chem. 175:479, 1948.
2. Alexander, F. Fundamental Concepts of Psychosomatic Research: Psychogenesis; Conversion; Specificity. Arch. Near. and Psych. 51:208, 1944.
3. Alexander, F.,
French, T. M., et al. Studies in Psychosomatic Medicine.
4. Alexander, F., and
French, T. M., et al. Psychoanalytic Therapy.
5. Alvarez, W. C.
Nervousness Indigestion and Pain.
6. Alvarez, W. C. Marked Abdominal Bloating Not Due to Gas but to a Neurosis of the Abdominal Wall. Trans. Asso. Amer. Physicians 1x:86, 1947.
7. Axefrod, H. E.,
Morgan, A. F., and Lepkovsky, S. The Fate of Tryptophane in
8. Bakwin, H., Reardon, H. S., Winn, J. S., Tenbrinck, M. S., Stem, M. L., and Engel, M. G. Relation of Lesions of the Tongue in Children to Niacin Deficiency. Am. J. Dis. Child. 74:657, 1947.
9. Barr, D. P. The Responsibilities of the Internist. Ann. Int. Med. 27:195, 1947.
10. Bauer, J. M., and Freyberg, R. H. Vitamin D Intoxication with Metastatic Calcification. J.A.M.A. 130:1208, 1946.
11. Bell, G. H., Scheer, B. T., and Deuel, H. J., Jr. Niacin Excretion in the Rat in Relation to Tryptophane, Pyridoxine, and Protein Content of the Diet. J. Nutr. 35:239, 1948.
12. Bennett, C. A.,
Waine, H., and Bauer, W. Changes in the Knee Joint at Various Ages.
13. Bergler, E. Synchronization of Neurotic Behavior Patterns. Am. J. Med. Sci. 210:470, 1945.
14. Bevans, M., and Tare, H. K. Lesions Following Use of Ertron in Rheumatoid Arthritis. Am. J. Path. 23:367, 1947.
15. Boland, E. W.
Psychogenic Rheumatism: The Musculoskeletal Expression of
Psychoneurosis. Ann. Rheum. Dis. (
16. Boland, E. W., and Corr, W. P. Psychogenic Rheumatism. J.A.M.A. 123:805, 1943.
17. Bond, H. W. Synthesis of Carboxyl-labeled Tryptophan from Hydantoin Containing Isotopic Carbon. J. Biol. Chem. 175:531, 1948.
18. Bowman, K. M. Modern Concept of the Neuroses. J.A.M.A. 132:555, 1946.
19. Brahdy, L., and Kahn, S. Trauma and Disease. Phila. Lea & Febiger. 1941.
20. Briggs, G.M. Influence of Gelatrn and Tryptophane on Nicotinic Acid Requirement of Chicks. J. Biol. Chem. 161:749, 1945.
21. Brody, M. Neurotic Manifestations of the Voice. Psychoanalyt. Quart. 12:371, 1943.
22. Brown, E. A., and Coitein, P. L. Psychiatric Studies in Clinical Allergy. Ann. Allergy 2:303, 1944.
23. Bruch, H. Psychological Aspects of Obesity. Bull. N.Y. Acad. Med. 24:73, 1948.
24. Buck, D. M., and Berg, C. P. Tryptophane Metabolism. XI. Changes in the Content of Tryptophane, Urea and Non-protein Nitrogen in the Blood and of Tryptophane in the Tissues after the Oral Administration of Tryptophane or Tryptophane Derivatives. J. Biol. Chem. 159:101, 1945.
25. Bull. National Research Council No.110. Enrichment of Flour and Bread, Nov.1944.
26. Burch, C., and Ray, T. Cardiovascular System as the Effector Organ in Psychosomatic Phenomena. J.A.M.A. 136:1011, 1948.
27. Cameron, D. E. Observations on Patterns of Anxiety. Am. J. Psychiat. 101:36, 1944.
28. Cecil, R. L. Textbook of Medicine. Phila. W. B. Saunders Co. 1947.
29. Chapman, W. P., Finesinger, J. E., Jones, C. M., and Cobb, S. Measurements of Pain Sensitivity in Patients with Psychoneurosis. Arch. Neur. and Psychiat. 57:321, 1947.
30. Cheldelin, V. H., and Williams, R. R. Studies of the Average American Diet. J. Nutr. 26:417, 1943.
31. Clarke, T. W. Allergy of the Central Nervous System. Ann. Allergy 2:189, 1944.
32. Cleckley, H. M., Sydenstricker, V.P., and Geeslin, L. E. Nicotinic Acid in the Treatment of Atypical Psychotic States Associated with Malnutrition. J.A.M.A. 112:2107, 1939.
33. Comroe, B. I. Arthritis and Allied Conditions. Phila. Lea & Febiger. 1944.
34. Cooper, W. A Simplified Ahibrometer. Ann. Surg. 114:316, 1941.
35. Cowgill, C. R. Recent Advances in our Knowledge of Vitamins. J. Mt. Sinai Hosp. 14:80, 1947.
36. Creed, R. S.,
Denny-Brown, D., Ecoles, J. C., Liddell, E.G. T., and Sherrington, C. S.
Reflex Activity of the Spinal Cord.
37. Daun, W. J., and Darby, W. J. The Appraisal of Nutritional Status (Nutriture) in Humans. Physiol. Rev. 25: 326, 1945.
38. Danowski, T. S., Winkler, A. W., and Peters, J. P. Tissue Calcification and Renal Failure Produced by Massive Dose Vitamin D Therapy of Arthritis. Ann. Int. Med. 23:22, 1945.
39. Darby, W. J. The Oral Manifestations of Iron Deficiency. J.A.M.A. 130:830, 1946.
40. Dees, S. C., and Lowenbach, H. The Electroencephalograms of Allergic Children. Ann. Allergy 6:99, 1948.
41. Drake, F. R. The latrogenic Factors in Illness. Am. J. Med. Sci. 215:103, 1948.
42. Drill, V. A., and Loomis, T. A. Production of Functional and Fatty Changes in the Liver by a Chronic Vitamin B Complex Deficiency, and Interrelationships with Protein Intake. J. Nutr. 35:333, 1948.
44. Elvehjem, C. A. Tryptophan and Niacin Relations and Their Implications to Human Nutrition. J. Am. Diet. Ass. 24:653, 1948.
45. Elvehjem, C. A., and Krehl, W. H. Imbalance and Dietary Interrelationships in Nutrition. J.A.M.A. 135:279, 1947.
46. Engel, C. L.,
Ferris, E. B., and
47. Engel, C.
48. Ershoff, B. H. Conditioning Factors in Nutritional Disease. Physiol. Rev. 28:107, 1948.
49. Fenichel, O. Nature and Classification of the So-called Psychosomatic Phenomena. Psychoanalyt. Quart. 14:287, 1945.
O. The Psychoanalytic Theory of Neurosis.
51. Field, H., Jr., and Robinson, W. D. The Absence of Reactions Following Therapeutic Doses of Nicotinic Acid Amide. Am. J. Med. Sci. 199:275, 1940.
52. Flind, J., and Barber, H. S. The Psychogenic Basis of Some So-called Rheumatic Pains. Quart. J. Med. 14:57, 1945.
53. Frank, A. Review of Some Fundamental Considerations in Psychotherapy. Dis. Nerv. System 8:69, 1947.
55. Freeman, C. L.
56. Freeman, S., Rhoads, P.S., and Yeager, L. B. Toxic Manifestations Associated with Prolonged Ertron Ingestion. J.A.M.A. 130:197, 1946.
57. Freund, H. A., Steiner, C., Leichtentritt, B., and Price, A. E. Nodular Polymyositis in Rheumatoid Arthritis. Science 101:202, 1945.
58. Freund, H. A., Steiner, C., Leichtentritt, B., and Price, A. E. Peripheral Nerves in Chronic Atrophic Arritis. J. Lab. and Clin. Med. 27: 1256, 1942.
59. Frost, J. W., Sunderman, F. W., and Leopold, I.S. Prolonged Hypercalcemia and Metastatic Calcification of the Sclera Following the Use of Vitamin D in the Treatment of Rheumatoid Artluitis. Am. J. Med. Sci. 214:639, 1947.
60. Citelson, M. The Role of Anxiety in Somatic Disease. Ann. Int. Med. 28:289, 1948.
61. Cliebe, P. A., and Kerr, W. J. Recognition of Emotional Factors in Allergic Manifestations. Am. J. Med. 3:607, 1947.
62. Cobell, O. Functions of Nicotinamide in Carbohydrate Metabolism. Z. Ces. Exptl. Med. 109:96, 1941.
63. Craubard, D. J., Kovacs, J., and Ritter, H. H. The Management of Destructive Arthritis of the Hip by Means of Intravenous Procaine. Ann. Int. Med. 28:1106, 1948.
64. Greenhill, J. P., and Freed, S. C. The Electrolyte Therapy of Premenstrual Distress. J.A.M.A. 117:504, 1941.
65. Croliman, A., Harrison, T. R., Mason, M. F., Baxter, J., Crampton, J., and Reichsman, F. Sodium Restriction in the Diet for Hypertension. J.A.M.A. 129:533, 1945.
66. Groom, D. Some Applications of Psychiatry in General Medicine. J.A.M.A. 135:403, 1947.
67. Halliday, J. L. The Concept of Psychosomatic Rheumatism. Ann. Int Med. 15:666, 1941.
68. Halliday, J. L. Psychological Factors in Rheumatism. Brit. Med. 3.1937, 1, 213 and 264.
69. Handler, P. The Effect of Excessive Nicotinamide Feeding on Rabbits and Guinea Pigs. J. Biol. Chem. 154:203, 1944.
70. Handler, P., and Dann, W. J The Inhibition of Rat Growth by Nicotinamide. J. BioL Chem. 146:357, 1942.
71. Handler, P., and Kohn, H. I. The Mechanism of Cozymase Synthesis in the Human Esythrceyte; a Comparison of the Roles of Nicotinic Acid and Nicotinarnide. J. Biol. Chem. 150:447, 1943.
72. Hankes, L. V., Henderson, L. M., Brickson, W. L., and Elvehjem, C. A. Effect of Amino Acids on the Growth of Rats on Niacin-Tryptophan-Deficient Rations. J. BioL Chem. 174:873, 1948.
73. Hansson, K. C. Body Mechanics and Posture. J.A.M.A. 128:947, 1945.
74. Harris, H.
75. Hart, A. D. Psychosomatic Diagnosis. J.A.M.A. 136:147, 1948.
76. Heidelberger, C., Cullberg, M. E., Morgan, A. F., and Lepkovsky, S. Concerning the Mechanism of the Mammalian Conversion of Tryptophan into Kynurenine, Kynurenic Acid, and Nicotinic Acid. J. BioL Chem. 175:471, 1948.
77. Hench, P.S., and
Boland, E. W. The Management of Chronic Arthritis and Other Rheumatic
Diseases among Soldiers of the
78. Hench, P.S., and
79. Hench, P.S., et al. Rheumatism and Arthritis: Review of American and English Literature of Recent Years (Ninth Rheumatism Review). Ann. Int. Med. 28:66 and 809, 1948.
80. Henderson, C. R., Wheeler, N. C., Johnson, H. C., Cogswell, R. C., Jr., Berryman, C. H., Ivy, A. C., Friedemann, T. E., and Youmans, J. B. Changes in Personality Appraisal Associated with a Restricted Intake of B Vitamins and Protein. Am. J. Med. Sci. 213:488, 1947.
81. Hill, L.W. Food Sensitivity in 100 Asthmatic Children. N.E.J. Med. 238:657, 1948.
82. Hoagland, C. L., Ward, S. M., and Shank, R. E. Synthesis of Coenzyme and Factor V in Erythrocytes, and the Excretion of Nicotinic Acid Derivatives in the Urine Following the Ingestion of Nicotinic Acid and Nicotinamide. J. Biol. Chem. 151:369, 1943.
83. Hoch, P.
H. (Ed.) Failures in Psychiatric Treatment.
84. Howorth,B. Dynamic Posture. J.A.M.A. 131:1398, 1946.
85. Hundley, J. M., and Bond, H. W. A Study of the Conversion of Isotopic Nicotinic Acid to Ni-Methylnicotinarnide. J. Biol. Chem. 173:513, 1948.
Hutchison, J. H. Non-articular Rheumatism in the Army: Symptomatology,
E. You Must Relax.
89. Johnson, A., Shapiro, L. B., and Alexander, F. Preliminary Report on a Psychosomatic Study of Rheumatoid Arthritis. Psycho-somatic Med. 9:295, 1947.
90. Johnson, B. C., Wiese, A. C., Mitchell, H. H., and Nevens, W. B. The Metabolism of Nicotinic Acid and Its Role in the Nutrition of the Calf. J. Biol. Chem. 167:729, 1947.
91. Jonsson, E. Arthralgia Due to Nervous Causes. Acta Med. Scand. 123:529, 1946.
92. Junqueira, P. B., and Schweigert, B. S. Urinary Excretion of Nicotinic Acid and Ni-methylnicotinamide by Rats Fed Tryptophan and Diets Deficient in Various B Vitamins. J. Biol. Chem. 175:535, 1948.
93. Karnosh, L. J. Psychosomatic Aspects of Allergy. Psychiat. Quart 18:618, 1944.
94. Karpman, B. Psychotherapy, Minor and Major. Quart. Rev. of Psychiat and Neur. 2:553, 1947.
95. Kamman, P., Beck, R. D., and Wiseman, R. D. Vitamin D ("Ertron') Therapy in Arthritis. J.A.M.A. 134:688, 1947.
96. Kaufman, W. Unpublished Observations.
W. The Common Form of Niacin Amide Deficiency Disease: Amacinamidosis.
98. Kennedy, A. F. The Problem of Psychogenesis in Non-articular Rheumatism. Rheumatism 4. 204, 1948.
99. Kern, R. A. The Role of Water Balance in the Clinical Manifestations of Allergy. Am. J. Med. Sci. 199:778, 1940.
100. Kraines, S. H. The Therapy of the Neuroses and Psychoses. Phila. Lea & Febiger, 1948.
101. Krehl, W. A., De la Huerga, J., and Elvehjem, C. A. Tryptophane Studies. I. The Effect of Niacin on the Utilization of Tryptophane. J. Biol. Chem. 164:551, 1946.
102. Krehl, W. A., Henderson, L. M., De la Huerga, J., and Elvehjem, C. A. Relation of Amino Acid Imbalance to Niacin-Tryptophane Deficiency in Crowing Rats. J. Biol. Chem. 166:531, 1946.
103. Krehl, W. A., Sarma, P.S., and Elvehjem, C. A. The Effect of Protein on the Nicotinic Acid and Tryptophane Requirement of the Crowing Rat. J. Biol. Chem. 162:403, 1946.
104. Kruse, H. D. A Concept of the Deficiency States. Milbank Mem. Fund Quart. 20:245, 1942.
105. Kruse, H. D. The Lingual Manifestations of Aniacinosis, with Especial Consideration of the Detection of Early Changes by Biomicroscopy. Milbank Mem. Fund Quart. 20:262, 1942.
106. Kruse, H. D. The Gingival Manifestations of Avitaminosis C, with Especial Consideration of the Detection of Early Changes by Biomicroscopy. Milbank Mem. Fund Quart. 20:290, 1942.
107. Kruse, H. D.
Medical Evaluation of Nutritional Status
108. Kruse, H. D. The Place of Nutrition in the Relationship Between Environment and Health. Milbank Mem. Fund Quart. 26:41, 1948.
109. Kruse, H. D.,
Bessey, O. A., Jolliffe, N., McLester, J. S., Tisdall, F. F., and Wilder, R.
M. Inadequate Diets and Nutritional Deficiencies in the
110. Kubie, L. S. The Basis of a Classification of Disorders from the Psychosomatic Standpoint. Bull. N.Y. Acad. Med. 20:46, 1944.
111. Kubie, L. S. The Nature of Psychotherapy. Bull. N.Y. Acad. Med. 19:183, 1943.
112. Kuiken, K. A., Lyman, C. M., and Hale, F. The Tryptophan Content of Meat. J. Biol. Chem. 171: 561, 1947.
113. Kurta, C. M., Orth, O. S., and Sepulveda, C. Vasodilatation in the Treatment of Rheumatoid Arthritis. Wisc. Med. J. 44: 761, 1945.
114. Kyhos, E. D., Cordon, E. S., Kimble, M. S., and Sevringhaus, E. L. The Minimum Ascorbic Acid Need of Adults. J. Nutr. 27:271, 1944.
115. Leblond, C. P., and Chaulin-Servmie're, J. Spontaneous Beriberi of the Monkey as Compared with Experimental Avitaminosis. Am. J. Med. Sci. 203:100, 1942.
116. Lepkovsky, S., Roboz, E., and Haagen-Smit, A. J. Xanthurenic Acid and Its Role in the Tryptophane Metabolism of Pyridoxine Deficient Rats. J. Biol. Chem. 149:195, 1943.
M. Psychotherapy in Medical Practice.
118. Lewis, H. B. Proteins in Nutrition. J.A.M.A. 138:207, 1948.
119. Ling, C., Hegsted, D. M., and Stare, F. J. The Effect of Pyridoxine Deficiency on the Tryptophan-Niacin Transformation in Rats. J. BioL Chem. 174:803, 1948.
120. Luecke, R. W., McMillen, W. N., Thorp, F., Jr., and Tull, C. The Relationship of Nicotinic Acid, Tryptophane and Protein in the Nutrition of the Pig. J. Nutr. 33:251, 1947.
121. Margolis, H.
M. Diagnosis and Treatment of Arthritis and Allied Disorders.
122. Masserman, J. H. Principles of Dynamic Psychiatry. Phila. W. B. Saunders Co. 1946.
123. McGregor, H. C. The Psychological Factor in Rheumatic Disease. J. Roy. Inst Pub. Health and Hygiene 4:169, 1941.
124. Merninger, K. Changing Concepts of Disease. Ann. Int Med. 29:318, 1948.
125. Menninger, W. C. The Problem of the Neurotic Patient. Ann. Int Med. 27:487, 1947.
126. Meyer,B.C. Psychosomatic Aspects of Stuttering. J. Nerv. Ment. Dis. 101:127, 1945.
127. Meyersburg, H. A. Senile Psychosis and Pellagra; A Report of Two Cases. N.E.J. Med. 233:173, 1945.
128. Miller, M.
M. Low Sodium Chloride Intake in the Treatment of Insomnia and
129. Mitchell, H. K., Nyc, J. F., and Owen, R. D. Utilization by the Rat of 3-hydroxyanthranilic Acid as a Substitute for Nicotinamide. J. Biol. Chem. 175:433, 1948.
B. Psychosomatics, p 678-722 in The Encyclopedia of Psychology.
131. Moritz, A. R. The Pathology of Trauma. Phila. Lea & Febiger. 1942.
132. Morrison, L. R., Short, C. L., Ludwig, A. O., and Schwab, R. S. The Neuromuscular System in Rheumatoid Arthritis; Electromyographic and Histologic Observations. Am. J. Med. Sci. 214:33, 1947.
134. Naide, M., Sayen, A., and Comroe, B. I. Characteristic Vascular Pattern in Patients with Rheumatoid Arthritis. Arch. Int Med. 76:139, 1945.
135. Neuwahi, F.
H. Action of Nicotinic Acid on Carbohydrate Metabolism. Lancet (
137. Nicholson, J. H., and Falk, A. Night Cramps in Young Men. N.E.J. Med. 238:556, 1945.
138. Nicholson, W. M. Emotional Factors in Obesity. Am. J. Med. Sci. 211:443, 1946. 39. Pelner, L. The Rapid Removal of Excess Joint Fluid by Acid Salts. Am. J. Med. Sci. 206: 498, 1943.
140. Pemberton, R. Developments in Arthritis. Am. J. Med. Sci. 209:364, 1945.
141. Pemberton, R., and Scull, C. W. Nutritional Aspects of the Treatment of Arthritis. Am. J. Med. Sci. 201:250, 1941.
142. Perera, G. A., and Blood, D. W. The Relationship of Sodium Chloride to Hypertension. J. Clin. Invest. 26:1109, 1947.
143. Perera, G. A., and Blood, D. W. Disturbance in Salt and Water Metabolism in Hypertension. Am. J. Med. 1:602, 1946.
144. Peters, J. P. The Role of Sodium in the Production of Edema. N.E. J. Med. 289:353, 1948.
145. Pickard, N. S. Rheumatoid Arthritis in Children. Arch. InL Med. 80:771, 1947.
146. Porter, C. C.,
147. ------ Primer on Arthritis. J.A.M.A. 119:1089, 1942.
148. Proc. of Asso.
for Research in Nerv. and Ment. Dis. The Role of Nutritional Deficiency
in Nervous and Mental Disease.
149. Pullen, R. L. Medical Diagnosis. Phila. W. B. Saunders Co. 1944.
150. Randolph, T. G. Food Allergy. Med. Clin. North Amer. 32:245, 1948.
151. Randolph, T. G. Allergic Headache: an Unusual Case of Milk Sensitivity. J.A.M.A. 126:430, 1944.
152. Randolph, T. G. Allergy as Causative Factor of Fatigue, Irritability and Behavior Problems in Children. J. Pediat 31:560, 1947.
153. Randolph, T. G. Fatigue and Weakness of Allergic Origin (Allergic Toxemia) to he Differentiated from "Nervous Fatigue" or Neurasthenia. Ann. Allergy 3:418, 1945.
154. Randolph, T. G., and Gibson, E. B. Blood Studies in Allergy II. The Presence in Allergic Disease of Atypical Lymphocytes and Symptoms Suggesting the Recovery Phase of Infectious Mononucleosis. Am. J. Med. Sci. 207:638, 1944.
155. Randolph, T. G., and Rawling, F. F. A. Blood Studies in Allergy V. Variation of Total Lenkocytes Following Test Feeding of Foods; An Appraisal of the Individual Food Test. Ann. Allergy 4:163, 1946.
156. Rennie, T. A. C. What Can the Practitioner Do in Treating the Neuroses? Bull. N.Y. Acad. Med. 22:23, 1946.
157. Rennie, T. A. C., and Howard, J. E. Hypoglycemia and Tension-Depression. Psychosomatic Med. 4:273, 1942.
158. Rinkel, J. Food Allergy I. The R6le of Food Allergy in Internal Medicine. Ann. Allergy 2:115, 1944.
159. ------ II. The Technique and Clinical Application of Individual Food Tests. Ann Allergy 2:504, 1944.
160. ----- IV. The Function and Clinical Application of the Rotary Diversified Diet J. Pediat 32:266, 1948.
161. Ropes, M. W., and Bauer, W. Rheumatoid Arthritis: Its Varied Clinical Manifestations. N.E. J. Med. 233:592 and 618, 1945.
162. Rosen, F., Huff, J. W., and Perlzweig, W. A. The Effect of Tryptophane on the Synthesis of Nicotinic Acid in the Rat. J. Biol. Chem. 163:843, 1946.
163. Rosen, F., Huff, J. W., and Perlzweig, W. A. The Role of B-6 Deficiency in the Tryptophane-Niacin Relationships in Rats. J. Nutr. 33:561, 1947.
164. Roth, L. J., Leffer, E., Hogness, J. R., and Langham, W. H. Studies on the Metabolism of Radioactive Nicotinic Acid and Nicotinamide in Mice. J. Biol. Chem. 176:249, 1948.
165. Rowe, A. H.
Allergic Toxemia and Migraine Due to Food Allergy.
166. Rowe, A. H. Clinical Allergy in the Nervous System. J. Nerv. and Ment. Dis. 99:834, 1944.
167. Rowe,A.H. Ehmination Diets and the Patient's Allergies. Phila. Lea & Febiger. 1944.
168. Ruesch, J.
Social Technique, Social Status, and Social Change in Illness, p. 117,
Personality in Nature, Society and Culture, ed. Kluckhohn, C., and Murray, H.
169. Ruesch,J. The Infantile Personality. Psychosomatic Med. 10:134, 1948.
170. Ruesch, J., and Bowman, K. M. Personality and Chronic Illness. J.A.M.A. 136:851, 1948.
171. Ry-Krisp Diets,
Eleventh Edition, Revised, Ralston Purina Company, St Lonis,
172. Sahynn, M.
(Ed.). Proteins and Amino Acids in Nutrition.
173. Salmon, W. D. Some Physiological Relationships of Protein, Fat, Choline, Methionine, Cystine, Nicotinic Acid and Tryptophane. J. Nutr. 38:155, 1947.
174. Sandstead, H. R., and Anderson, R. K Nutrition Studies. I. Description of Physical Signs Possibly Related to Nutritional Status. Pub. Health Rep. 62:1073, 1947.
175. Saphir,W. Chronic Hypochioremia Simulating Psychoneurosis. J.A.M.A. 129:510, 1945.
176. Sarett, H.P., Huff,
J. W., and Perlzweig, W. A. Studies in Nicotinic Acid Metabolism. I. The Fate
of Nicotinic Acid in
177. Sarett, H.P.
Studies in Nicotinic Acid Metabolism. II. The Fate of Nicotinic Acid in
178. Sarett, H.P., and Goldsmith, G. A. The Effect of Trytophane on the Excretion of Nicotinic Acid Derivatives in Humans. J. Biol. Chem. 167:293, 1947.
179. Sarett, H.P., and Perlzweig, W. A. The Effect of Protein and B-Vitamin Levels of the Diet upon the Tissue Content and Balance of Riboflavin and Nicotinic Acid in Rats. J. Nutr. 25:173, 1943.
180. Sargent, M. Psychosomatic Backache. N.E. J. Med. 234:427, 1946.
181. Saul, L. J. Emotional Maturity. Phila. J. B. Lippincott Co. 1947.
182. Schilling, R. F., and Musser, M. J. Pain Reaction Thresholds in Psychoneurotic Patients. Am. J. Med. Sci. 215:195, 1948.
184. Schwartz,A.B. Childhood Manifestations of Allergic Adults: Prelude to Allergy. J. Pediat. 33:202, 1948.
185. Schweigeri, B. S. The Role of Vitamin B-6 in the Synthesis of Tryptophane from Indole and Anthranilic Acid by Lactobacillus Arabinosus. J. Biol. Chem. 168:283, 1947.
186. Schweigert, B. S., German, H. L., and Garber, M. J. Synthesis of Nicotinic Acid from Tryptophan by the Developing Chick Embryo. J. Biol. Chem. 174:383, 1948.
187. Schweigert, B. S., and Pearson, P. B. Effect of Vitamin B6 Deficiency on the Ability of Rats and Mice to Convert Tryptophane to N(1) - methylnicotinamide and Nicotinic Acid. J. Biol. Chem. 168: 555, 1947.
188. Schweigert, B. S., and Pearson, P. B. Further Studies on the Metabolism of Tryptophan and Nicotinic Acid by the Rat and Other Animals. J. Biol. Chem. 172:485, 1948.
189. Scull, C. W., and Pemberton, R. The Influence of Dietetic and Other Factors on the Swelling of Tissues in Arthritis. Ann. Int. Med. 8:1247, 1935.
190. Selye, H., Sylvester, O., Hall, C. E., and Leblond, C. P. Hormonal Production of Arthritis. J.A.M.A. 124:201, 1944.
191. Sevringhaus, E. L., and Kyhos, E. D. Reversal of Lingual Atrophic Changes with Nicotinamide Therapy. Arch. Int. Med. 76:31, 1945.
192. Shaw, J. H., Phillips, P. H., and Elvehjem, C. A. Acute and Chronic Ascorbic Acid Deficiencies in the Rhesus Monkey. J. Nutr.29:365, 1945.
193. Sherman, H. C.
The Science of Nutrition.
194. Sherringron, C.
S. The Integrative Action of the Central Nervous System.
195. Short, C. L. Arthritis in the Mediterranean Theatre of Operations. I. Incidence of Joint Disease. Clinical Description of Rheumatoid Arthritis. N.E.J. Med. 236:383, 1947.
196.. ------ II. Clinical Description of Hypertrophic Arthritis, Arthralgia and Psychogenic Rheumatism. N.E. J. Med. 238:429, 1947.
197. ------ III. Clinical Description of Infections and Other Types of Arthritis. N.E. J. Med. 238:468, 1947.
198. Short, C. L., and Bauer, W. The Course of Rheumatoid Arthritis in Patients Receiving Simple Medical and Orthopedic Measures. N.E. J. Med. 238:142, 1948.
199. Shulman, M. H. Prophylaxis Against Allergy. N.E. J. Med. 239:391, 1948.
200. Simms, H. S. Logarithmic Increase in Mortality as a Manifestation of Aging. J. Geront. 1:9, 1946.
201. Singal, S. A., Briggs, A. P., Sydenstricker, V.P., and Littlejohn, J. M. The Effect of Tryptophane on the Urinary Excretion of Nicotinic Acid in Rats. J. Biol. Chem. 166:573, 1946.
202. Singal, S. A., Sydenstricker, V.P., and Littlejohn, J. M.
a. The Effect of Some Amino Acids on the Growth and Nicotinic Acid Storage of Rats on Low Casein Diets. J. Biol. Chem. 171:203, 1947.
b. The Role of Tryptophan in the Nutrition of Dogs on Nicotinic Acid-deficient Diets. J. Biol. Chem. 176:1051, 1948.
c. Further Studies on the Effect of Some Amino Acids on the Growth and Nicotinic Acid Storage of Rats on Low Casein Diets. J. Biol. Chem. 176:1063, 1948.
d. The Nicotinic Acid Content of Tissues of Rats on Corn Rations. J. Biol. Chem. 176:1069, 1948.
203. Solomon, M. Psychophysiologic Interrelationships. Arch. Neur. and Psychiat. 55:678, 1946.
204. Spector. H. The Metabolic Interrelationship Between Tryptophan, Pyridoxine and Nicotinic Acid; Forced Feeding Studies in Rats. J. Biol. Chem. 173:659, 1948.
205. Spector, H., and Mitchell, H. H. Paired Feeding in the Study of the Counteraction by Nicotinic Acid and Tryptophane of the Growth-Depressing Effect of Corn in Rats. J. Biol. Chem. 165: 37, 1946.
206. Spies, T. D., Aring, C. D., Gelperin, J., and Bean, W. B. The Mental Symptoms of Pellagra: Their Relief with Nicotinic Acid. Am. J. Med. Sci. 196:461, 1938.
207. Stanfleld, C. E. Psychotherapy: an Orientation for Non-psychiatrists. Am. J. Med. Sci. 216:97, 1948.
208. Stannus, H. S. Disorders of the Nervous System Due to Malnutrition. Brit. Med. J. 1948, 1, 342.
209. Stead, E. A., Jr., and Warren, J. V Clinical Significance of Hyperventilation; the Role of Hyperventilation in the Production, Diagnosis and Treatment of Certain Anxiety Symptoms. Am. J. Med. Sci. 206:183, 1943.
210. Stecher, R. M., and Karnosh, L. J. Heberden's Nodes VI. The Effect of Nerve Injury Upon the Formation of Degenerative Joint Disease of the Fingers. Am. J. Med. Sci. 213:181, 1947.
211. Steinbrocker, 0. Therapeutic Injections in Painful Musculoskeletal Disorders. J.A.M.A. 125: 897, 1944.
212. Stetten,D. Studies in Intermediary Metabolism Conducted with the Md of Isotopic Tracers. Bull. N.Y. Acad. Med. 24:87, 1948.
213. Stevenson, L. D., and Alvord, E. C. Allergy in Nervous System. Review of Literature. Am. J. Med. 2:614, 1947.
214. Sydenstricker, V.P., and Cleckley, H. M. The Effect of Nicotinic Acid in Stupor, Lethargy and Various Other Psychiatric Disorders. Am. J. Psychiat. 98:88, 1941.
215. Tarachow, S. The Syndrome of Inhibition. Psychiat. Quart. 21:238, 1947.
216. Thorn, G. W., and Emerson, K., Jr. The Role of Gonadal and Adrenal Cortical Hormones in the Production of Edema. Ann. Int. Med. 14:757, 1940.
217. Travell, J., and Bigelow, N. H. Role of Somatic Trigger Areas in the Patterns of Hysteria. Psychosomat. Med. 9:358, 1947.
218. Tumbull, J. A. Why the Failures in the Treatment of Allergy. Am. J. Dig. Dis. 11:363, 1944.
219. Turnbull,J.A. Changes in Sensitivity to Allergenic Foods in Arthritis. Am. J. Dig. Dis. 11:182, 1944.
220. Tumbull, J. A. The Tired, Weak, Exhausted, Depressed Patient. Am. J. Dig. Dis. 10:218, 1943.
221. Turnbull, J. A. Study of 127 Cases of Arthritis (With Notes on Gastro-Intestinal Features). Am. J. Dig. Dis. 11:122, 1944.
222. Urbach, E. Possible Endogenous-Allergic Mechanism of Hormonal Arthritis. J.A.M.A. 124:731, 1944.
223. Urbach, E.,
and Gottlieb, P. M. Allergy.
224. Waggoner, R. W. Psychoneurosis, its Significance in General Practice. J.A.M.A. 134:779, 1947.
225. Wagoner, G.,
Rosenthal, 0., and Bowie, M. A. Studies of the Cell in
226. Wald, G., and
227. Wallis, A. D. Rheumatoid Arthritis. I. Introduction to a Study of Its Pathogenesis. Am. J. Med. Sci. 212:713, 1946.
228. ------ II. Non-specific Serologic Reactions. Am. J. Med. Sci. 212:716, 1946.
229. ------ Ill. The Pneumococcus Antibodies. Am. J. Med. Sci. 212:718, 1946.
230. ------ IV. Hemolytic Streptococcus Precipitin Reactions. Am. J. Med. Sci. 213:87, 1947.
231. ------ V. The Agglutination of Hemolytic Streptococci. Am. J. Med. Sci. 213:94, 1947.
232. Weiss, E. Psychogenic Rheumatism. Ann. Int. Med. 26:890, 1947.
233. Weiss, E. Psychosomatic Aspects of Allergic Disorders. Bull. N.Y. Acad. Med. 23:604, 1947.
234. Weiss, E. Psychotherapy in Everyday Practice. J.A.M.A. 137:442, 1948.
235 Weiss, E., and English, O.S. Psychosomatic Medicine. Phila. W. B. Saunders Co. 1943.
236. Whitehorn, J. C. Guide to Interviewing and Clinical Personality Study. Arch. Neur. and Psychiat. 52:197, 1944.
237. Wilson G., and Rupp, C., Jr. Present Trends in the Practice of Neurology. J.A,M.A. 133:509, 1947.
238 Wintrobe, M. M., Stein, H. J., Follis, R. H., Jr., and Humphreys, S. Nicotinic Acid and the Level of Protein Intake in the Nutrition of the Pig. J. Nutr. 30:395, 1945.
239. Witmer, H. L.
(ed.) Teaching Psychotherapeutic Medicine.
240. Wolf, S. Sustained Contraction of the Diaphragm, the Mechanism of a Common Type of Dyspnea and Precordial Pain. J. Clin. Invest. 26:1201, 1947.
241. Wolff, H. G. Protective Reaction Patterns and Disease. Ann. Int. Med. 27:944, 1947.
Wolff,H.G. Headache and Other Pain.
243. Wolff, H. G., and Hardy, J. D. On the Nature of Pain. Physiol. Rev. 27:167, 1947.
244. Woolley, D. W. Production of Nicotinic Acid Deficiency with 3-Acetylpyridine, the Ketone Analogue of Nicotinic Acid. J. Biol. Chem. 157:455, 1945.
245. Woolley, D. W. Recent Advances in the Study of Biological Competition Between Structurally Related Compounds. Phys. Rev. 27:308, 1947.
246. Woolley, D. W. Reversal by Tryptophane of the Biological Effects of 3-Acetylpyridine. J. Biol. Chem. 162:179, 1946.
247. Woolley, D. W. The Occurrence of a "Pellagragenic" Agent in Corn. J. BioL Chem. 163:773, 1946.
248. Wright, H.P.
Psychogenic Arthralgia. Ann. Rheum. Dis. (
This monograph records certain clinical observations which I have made over a period of years in the course of the private practice of internal medicine. As will be demonstrated by objective measurement, joint dysfunction (impaired joint mobility) was exceedingly prevalent among the patients studied. It will be seen that the common form of joint dysfunction was corrected or ameliorated in time by adequate niacinamide therapy, and recurred in time when adequate niacinamide therapy was discontinued.
While the diagnosis and treatment of uncomplicated joint dysfunction presented few difficulties, the patient with joint dysfunction often was troubled by the articular and non-articular symptoms of four commonly occurring complicating syndromes which required successful therapy concurrently with the niacinamide treatment of joint dysfunction if the patient was to feel well. For this reason, these complicating syndromes and their treatment are described in some detail.
It is hoped that the methods of study and treatment presented in this volume will be of use to other physicians in the medical management of patients who have joint dysfunction alone, or joint dysfunction and one or more of the four complicating syndromes.
I am greatly indebted to Dr. Robert Sterling Palmer in many ways, especially for his critical reading of the manuscript, for his constructive suggestions and for his wise counsel. Thanks are due to Dr. Louis H. Cohen, who read the manuscript critically and gave helpful suggestions. I am grateful to my wife, Charlotte S. Kaufman, for her encouragement and valuable assistance in all phases of this work.
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